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PHARMACEUTICAL STANDARDIZATION
Year : 2011  |  Volume : 32  |  Issue : 1  |  Page : 109-115

Standard manufacturing process of Makaradhwaja prepared by Swarna Patra-Varkha and Bhasma


1 Ph.D.Scholar, Department of Rasashastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
2 Reader, Department of Rasashastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, India
3 Director, Research and Development, SDM College of Ayurveda, Udupi, Karnataka, India
4 Professor and Head, Department of Rasashastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India

Correspondence Address:
Sanjay Khedekar
Ph.D. Scholar, Department of R.S. and B.K. I.P.G.T. and R.A., Gujarat Ayurved University Jamnagar, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-8520.85741

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Makaradhwaja is an important Kupipakwa Rasayana. It is prepared by using Swarna (gold), Parada (mercury) and Gandhaka (sulfur) in different ratios, i.e. 1:8:16, 1:8:24 and 1:2:4, respectively. The amount of Gandhaka in the Jarana process is directly proportional to the increase in therapeutic efficacy and reduces the toxicity of the product. Specific temperature pattern for the preparation of Makaradhwaja has been followed. In the present study Swarna, Parada and Gandhaka were taken in the ratio 1:8:24, respectively, and 12 h of heating for a specified amount of Kajjali (i.e., 400 g) in a Kacha Kupi 1/3 rd of its capacity. There are some controversies regarding the form of Swarna (i.e., Swarna Patra Swarna Varkha or Swarna Bhasma) used in the preparation of Makaradhwaja. Therefore, in the present study, the samples of Makaradhwaja were prepared by Swarna Patra, Varkha and Bhasma in different batches. It was found that the use of Varkha produced a good-quality product along with the maximum amount of gold, i.e. 268 ppm, in comparison with Patra, i.e. 131 ppm, and Bhasma, i.e. 19 ppm, respectively.


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