| RESEARCH ARTICLE |
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| Year : 2009 | Volume
: 30
| Issue : 3 | Page : 279-283 |
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Vacha (Acorus calamus) as an Ayurvedic Premedicant
DN Pande1, SK Mishra2
1 Incharge, Section of Sangyaharan, Dept.of Shalya Tantra, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
2 Consultant Anaesthesiologist, Gopiganj, Bhadohi, (U.P.), India
Correspondence Address:
D N Pande
Incharge, Section of Sangyaharan, Dept.of Shalya Tantra, Institute of Medical Sciences, Banaras Hindu University, Varanasi
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Previously many indigenous herbal drugs mentioned in Ayurvedic literature were experimentally screened on the animals and were also studied clinically on the patients as pre-anesthetic medication drug such as Brahmi, Sankhapushpi, Mandukparni, Jatamansi etc. Modern research workers had also proved their usefulness in the treatment of nervous and mental diseases. In the same chain of research work, Vacha was selected for this study and was used in the form of Ghanasatva. The clinical trial was carried on 40 healthy patients. The patients were divided into two groups randomly. The control and trial groups included 20 patients each of narrow age and weight distribution. The patients of group I (Control) were premedicated with Inj. Glycopyrrolate 0.2 mg IM and Tab. Phenergan 50 mg orally with one ounce of plain water. The patients of group II (Trial) were premedicated with Inj. Glycopyrrolate 0.2 mg I.M. and Vacha (Ghansatva) orally in recommended doses with one ounce of plain water 90 minutes prior to induction of anaesthesia. A standard anesthetic technique with pre oxygenation for 3 minutes & Nitrous oxide with Ether inhalation by spontaneous ventilation with Maggill's open circuit (Boyle's apparatus) was used. The following parameters were used to see the efficacy of the drug : Psychophysical effect before induction of anaesthesia, Cardio-respiratory and other reflex response during the course of subsequent anaesthesia & Post operative sickness in immediate post operative period up to two hours. On the basis of observations, it was concluded that Vacha controls the raised body temperature, produces good sedation and it may be helpful in the patients with preexisting hyperthermia. It does not produce any C.V.S. & Respiratory depression. |
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