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| LETTER TO EDITOR |
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| Year : 2018 | Volume
: 39
| Issue : 4 | Page : 256 |
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Kaphaja, Kapha-Pittaja Prakriti, methylenetetrahydrofolate reductase C677T allele and type 2 diabetes
Beuy Joob1, Viroj Wiwanitkit2
1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Department of Community Medicine, Dr. DY Patil University, Pune, Maharashtra, India
| Date of Web Publication | 5-Jul-2019 |
Correspondence Address:
Dr. Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
Thailand
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ayu.AYU_44_19
How to cite this article:
Joob B, Wiwanitkit V. Kaphaja, Kapha-Pittaja Prakriti, methylenetetrahydrofolate reductase C677T allele and type 2 diabetes. AYU 2018;39:256 |
Dear Editor,
We read the publication on “Association of Kaphaja and Kapha-Pittaja Prakriti and methylenetetrahydrofolate reductase C677T allele with type 2 diabetes” with a great interest.[1] Gupta et al. noted that “The present study gives a strong clue for the association of Prakriti (body constitutional) and clinical phenotype.[1]” Indeed, this finding is interesting and can confirm that the classical knowledge is still presently merit for explanation of the common metabolic disease. However, there are some points that should be noted. The diabetic patient might have other concurrent problems. Metabolic syndrome (diabetes mellitus, dyslipidemia, hypertension and obesity) is very common worldwide. The other common diseases in the group of metabolic syndrome might affect the relationship between Kaphaja and Kapha-Pittaja Prakriti and methylenetetrahydrofolate reductase C677T allele. Furthermore, aging is another important factor that is related to Kaphaja and Kapha-Pittaja Prakriti. The pattern of phenotype might be different at different ages.[2] In addition, there are also other common genetic factors that are related to diabetes mellitus.[3] The association between Kaphaja and Kapha-Pittaja Prakriti and clinical phenotype might be affected by those genetic factors. Finally, it should be noted that a holistic concern bio-psycho-social-spiritual dimension or Vataja, Pittaja and Kaphaja dimension should be mentioned if we would like to discuss on a phenotype of a medical problem. For diabetes pathophysiology, the recent reports showed that Vata has more influence than Pitta and Kapha on insult-related phenotype in diabetic patients.[4]
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
 References | |  |
| 1. | Gupta A, Ali A, Tewari P, Agrawal NK, Patel R, Byadgi PS, et al. Association of kaphaja and Kapha-pittaja prakriti and methylenetetrahydrofolate reductase C677T allele with type 2 diabetes. Ayu 2018;39:146-50.  [ PUBMED] [Full text] |
| 2. | Purvya MC, Meena MS. A review on role of prakriti in aging. Ayu 2011;32:20-4. [ PUBMED] [Full text] |
| 3. | Cohen D, Haguenauer-Cohen O, Hors J, Deschamps I, Dausset J. Molecular genetics of juvenile diabetes. Journ Annu Diabetol Hotel Dieu 1985;21:157-69. |
| 4. | Chandola HM, Tripathi SN, Udupa KN. Variations in the progenesis of maturity onset diabetes according to body constitution. Anc Sci Life 1994;13:293-301. |
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