In Ayurveda the metals are known and used as Rasayana and as therapeutic agents since ancient times (800 -1000 BC). Their use in therapeutic was very limited due to their non conversion into suitable pharmaceutical form i.e. these were in fine powder only which was made treating those to red hot state and quenching into some of the herbal extractive. Only six metals (Gold, Silver, Copper, Iron, Tin and Lead) had been recognized for their medicinal values and used internally. In 8 th/9th century AD and onwards, when the development of Rasashastra has taken place in the field of Ayurveda, many new pharmaceutical processing techniques along with equipments and drugs were evolved and developed which have revolutionized Ayurvedic pharmaceutical technology to such anexent that by using that metals could be converted to such a form which is considered must suitable for their internal use in the body. Loknath rasa is mostly indicated in the disease like Yakrtplihodara (Hepato - spleeno - megaly), Gulma (Abdominal tumour) and Sotha (Inflammation), though it is available in the market but quality may not be up to standard and if the same is used internally produces some toxic effects on the body. Loknath rasa was prepared in two different methods i.e. Gujaputa and Electric muffle furnace. Muffle furnace method is found good than Gujaputa. According to adulteration point of view, Loknath rasa was prepared separately by mardan (rubbing) on nagvalli rasa (Piper betel Linn) and tap water; and compared the analytical values. Iron, Aluminium and Calcium values are found higher in the Jala (water) mardan while Mercury, Sulphar, Magnesium and Sulphate are found less in different method of preparation.

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Sthaulya is a predominant metabolic disorder. It is described by Acharya Charaka in Ashtaunindita Purusha . In the present Study Navaka guggulu is taken for Clinical trial which is referred from Bhaishajya Ratnawali " Medoroga Chikitsa( 39/43). It mainly contains drugs like Sunthi, Marich Pippali, Chitraka, Haritaki, Bibhitaki, Amalaki, Musta, Vidanga and Shuddha guggulu. Almost all the drugs are having Katu rasa, laghu ruksha guna, Ushna veerya, Katu vipaka and Kapha Vata Shamaka properties which may be helpful in disintegrating the Samprapati of Sthaulya. Navaka guggulu showed encouraging results in reduction of weight, skin fold thickness, body circumference and associated signs and symptoms.

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Ayurveda mentions diet (Ahara), sleep (Nidra) and Brahmacharya as the Tripods of life. Sex is a basic instinct, but sexual behaviour is a learned ability. The concept of Kama reveals that the recreational aspects like pleasure are equally important to its procreation aspects. Shukra Avrita Vata is a clinical condition characterized by Shukra Avega, Shukra Ativega and Nishphalatvam. It can be compared to Premature ejaculation (PE) a psychosexual orgasmic disorder. Sex lies in the mind and not between the legs. - Sigmund Freud. In the course of research involvement of the psycho-neuro- sexual axis (Vata, Shukra and Mana) was observed. Keeping this in mind 60 subjects were subjected to a Single blind placebo controlled clinical study consisting of three randomized parallel groups of 20 subjects each to tackle the problem on psychological (Group A- Placebo + psychological counseling), psychobiological (Group B- Rasayana Yoga + psychological counseling) and neuro-bio-psychological (Group C- Rasayana Yoga + Shirodhara + psychological counseling) platforms. Though statistically highly significant results, were observed in all three groups. The improvement in Group C was better compared to Group B with regards to Intra-vaginal ejaculatory latency time, voluntary control over ejaculation, patient satisfaction, performance anxiety and number of penile thrusts. In terms of partner satisfaction improvement in Group B was better compared to Group C.

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Psoriasis is a common skin disease affecting about 1-2% of general population. The word psoriasis is derived from the Greek word "Psora" and "Iasis". Psora means Itch or scale and lasis means condition. Acharya Charak has described the involvement of Vata and Kapha in Ekkushtha. In the present study Ekkushta is compared with psoriasis due to its maximum resemblance with it. The trial drugs in the present study are Pathyadhya Vatak and Vidangadi Lepa which have not been studied on Psoriasis till date as per our Knowledge. The effect of Placebo was also assessed to understand the Psychosomatic nature of the disease. The results of combination of Pathyadaya Vatak and Vidangadi lepa were highly encouraging.

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A randomized, double blind, standard control study was done on 60 patients of hyperlipidaemia and the role of Ayurvedic drugs as Panchatikta Ghana (Combination of Adhatoda vasica, Azadirachta indica, Tinospora cordifolia, Solanum xanthocarpum, Trichosanthes dioica) and Shuddha Guggulu (Commiphora mukul) has been evaluated by dividing the patients in two groups. It was found that Shuddha Guggulu is superior to Panchatikta Ghana in reducing the lipids i.e. S.Cholesterol, S.Triglyceride, and S.VLDL. Both the drugs have significant effect in reducing the symptoms of Medodushti and in reduction of objective parameters like weight, BMI, body circumferences such as chest, abdomen, hip and pelvis circumferences etc. and skin fold thickness as Biceps, Triceps and Abdominal skin fold thickness.

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