Sandhigata Vata is the commonest form of articular disorder. It is a type of Vatavyadhi which mainly occurs in Vriddhavastha due to Dhatukshaya, which limits everyday activities such as walking, dressing, bathing etc. thus making patient disabled / handicapped. It being a Vatavyadhi, located in Marmasthisandhi and its occurrence in old age makes it Kashtasadhya. Vata Dosha plays main role in the disease. Shula Pradhana Vedana is the cardinal feature of the disease associated with Sandhishotha with Vata Purna Druti Sparsha, lack of movements of the joints or painful movement of the joints. In this study total 49 patients having the complaints of Osteoarthritis were randomly divided into 2 groups. In Group A, patients were treated with Panchatikta Ghrita Guggulu Vati along with Abhyanga and Nadi Swedana and in group B patients were treated with only Abhyanga and Nadi Swedana. The data shows that Panchatikta Ghrita Guggulu along with local Abhyanga and Nadi Swedana i.e. group A has provided better relief in the disease Sandhigata Vata.

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AIDS is one of the serious global health concerns caused by Human Immuno Deficiency(HIV) virus and is predominantly a sexually transmitted disease. Currently there is no vaccine or cure for AIDS still Anti Retroviral Therapy (ART) is successful. It reduces both the mortality and the morbidity of HIV infection, but is expensive and inaccessible in many countries. However intense the therapy may be, HIV virus is rarely eliminated, and drug resistance is a major setback during long-term therapy. The development of new drugs and strategies and exploring alternative systems of medicine for antiviral herbs or drugs is the need of the age to improve treatment outcomes. Ayurveda describes many diseases which incorporate HIV like illness e.g. Rajayakshma, Ojo Kshaya, Sannipata jwara etc. HIV infection affects multisystems, chiefly the Immune System which can be correlated to Ojo Kshaya. Rasayana Chikitsa is the frontline therapy employed to treat Ojus disorders. Therefore Shilajatu (Mineral pitch), Centella asiatica (Mandukaparni), Tinospora cordifolia (Guduchi) and Emblica officinalis (Amalaki), well known for their Immuno-modulator and antioxidant properties were selected to evaluate their role on immune system. The study was carried on 20 patients from OPD and IPD of Kayachikitsa, S.S.Hospital, IMS, BHU and was randomly allocated into Treated group (Shilajatu+ART) and Control group (ART). Treated Group responded better to ART both clinically and biochemically. The results show that Shilajatu decreases the recurrent resistance of HIV virus to ART and improves the outcome of the therapy

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Poly Cystic Ovarian Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age, resulting from insulin resistance and the compensatory hyperinsulinemia. This results in adverse effect on multiple organ systems and may result in alteration in serum lipids, anovulation, abnormal uterine bleeding and infertility. According to Ayurvedic view PCOS can be correlated with Aarthava Kshaya. It was revealed that most of subfertility patients who were presented Osuki Ayurveda Centre suffered from the PCOS. Therefore the present study was carried out for the clinical evaluation of the efficacy of Ayurveda treatment regimen on subfertility with PCOS. Total 40 patients were selected by using purposive sampling method. According to the Ayurveda theories of Shodhana, Shamana and Tarpana, the treatment was conducted in 3 stages for the duration of 6 months. The response to the treatment was recorded and therapeutic effects were evaluated by symptomatic relief and through Trans Vaginal Scan and LH, FSH hormone levels. The results revealed that, subfertility due to PCOS can be cured successfully by using this Ayurveda treatment regimen.

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Generally, skin diseases run a chronic course and the recurrence is very common. Mandip and Chandola (2009) reported that Shirishadi Decoction administered orally and simultaneously Snuhyadi Lepa applied externally to the patients of Vicharchika (Eczema) provided complete remission to 18.2% patients, marked improvement to 42.4% patients and moderate improvement to 36.4% patients but the recurrence rate was very high i.e. 80%. Charaka, in the context of the treatment of Apasmara mentions that in all the chronic diseases, Rasayana drugs should be prescribed. As eczema is a chronic disease and its recurrences are very common, therefore, it was thought desirable to evaluate the role of the Rasayana drugs in the cure and prevention of the recurrence of Vicharchika (Eczema). In this study, total 38 patients of Vicharchika (Eczema) were registered, among which 31 patients completed the full course of treatment. These patients were first subjected to Koshtha Shuddhi done with Aragvadha (Cassia fistula) Hima administered orally at bedtime for initial eight days. Thereafter 30 ml of Shirishadi Decoction and 6 gm of Guduchi (Tinospora cardifolia) and Bhringaraja (Eclipta alba) powder was given with Ghrita. Both the drugs were given twice daily after meals orally. Simultaneously, Snuhyadi Lepa was applied on the eczematous lesions. Results of the study showed that addition of Rasayana drugs provided complete remission to 22.6% and checked the recurrence of the disease in the 89.5% patients of Vicharchika (Eczema).

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Kaphaja Shira Shula is one of the Shiro Roga. Chronic sinusitis is inflammation of the sinuses behind the forehead, cheeks, and eyes, which continues for a long time or keeps recurring. Kaphaja Shira Shula can be correlated with Chronic Sinusitis. The decoction of Katuwelbatu Deduru Katuka is mentioned in Watika Prakaranaya, a book on Sri Lankan Traditional Medicine. The ingredients of this decoction are Solanum xanthocarpum, Cuminum cyminum, Nigella sativa, Picroihiza kurrota and Clerodendrum serratum . But in this study Saussurea lappa is used instead of C. serratum with the experience of traditional physician, Weerasinghe. Aim of this study was to scientifically evaluate the efficacy of this decoction in Kaphaja Shira Shula. Eighty patients suffering from Chronic sinusitis were selected from Ayurveda Teaching Hospital, Borella, Sri Lanka and randomly divided into two groups. X-ray of Para nasal sinuses and total white cell count before treatment and after treatment were recorded. Group one was treated with 120 ml of decoction of Katuwelbatu Deduru Katuka and Group two with 120 ml of placebo twice a day for twenty one days. Partial and complete symptomatic relief and reduction in esinophil count in the blood were observed in the treated group. It is observed that decoction of Katuwelbatu Deduru Katukadiya can be used in treatment of Kaphaja Shira Shula (Chronic sinusitis) effectively.

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'Basti' is compared with conventional enema due to its similarity in procedure of administration. But in effect enema is a simple evacuation technique, whereas 'Basti' is a therapeutic measure considered as 'Ardha Chikitsa' i.e half therapy in the disease management. Constitution of 'Basti dravya' formulation specifically 'Aasthaapana Basti' has a direct impact on the end result of 'Basti' therapy. A systematic stepwise procedure of preparation of 'Aasthaapana Basti' is described in Ayurvedic Classics. The present study evaluates the significance of this procedure through standardization of 'Maadhutailika Basti', a type and standard of 'Aasthaapana Basti'. Four samples of 'Aasthaapana Basti' including the classical one were prepared for this study by replacement, exclusion and supplementation of honey in the formulation. A comparative study of physico-chemical characteristics of these samples was carried out. The stability of the constitution of 'Maadhutailika Basti' was also studied to assess the role of honey as a natural emulsifying agent. The study underlines the significance of the procedure described in the classics emphasizing the role of honey as a natural emulsifying agent in standardization of 'Maadhutailika Basti'.

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The study was conducted in 30 clinically diagnosed patients of Anidra (Insomnia) with an objective of clinical evaluation of the efficacy of Shirodhara and Tab. Insomrid (proposed herbal formulation) in the management of Anidra (Insomnia). These patients were randomly divided into three groups of 10 patients each. In was observed that the patients of Group III treated with Tab. Insomrid and Shirodhara with milk showed highly significant improvements, whereas the Group II treated with Shirodhara and Group I treated with Tab. Insomrid also showed significant improvements. No adverse effects were noted in any of the patients during the trial period.

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The objective of the present research was to study the efficacy of Laksha Guggulu, Snehana, Swedana & Traction in the management of Osteoarthritis (Knee joint). For the present work, 30 clinically diagnosed patients were selected and randomly divided into three groups. Group A treated with Laksha Guggulu orally, Group B treated with snehana & swedana traction, Group C treated with Laksha Guggulu, Snehana, Swedana & Knee Joint Traction. The various criteria worked upon were joint pain, oedema, tenderness, restriction of joint movement, stiffness, local crepitation, walking distance. Significant results were obtained on pain in joint movement, restriction in joint movement, joint stiffness , local crepitation nearly in all the groups with best result in combined group or group C.

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Ayurveda the science of life, since its origin is serving the mankind throughout in health & disease state of life. Shalakyatantra, one of its specialized branch deals with the science of Ophthalmology, Otorhinolaryngology, Orodental surgery & Head; was contributed and developed by Rajrishi Nimi, the King of Videha , who was a colleague of Atreya, Punarvasu, Dhanwantri, Bharadwaja, Kashyapa etc. The available literature related to this speciality is reproduced from original text of Nimitantra in Uttartantra of Sushruta samhita. So Rajrishi Nimi deserves all the credit and regards for Shalakyatantra and for being the first eye surgeon on this earth. The fact regarding the technique of cataract surgery adopted by ancient surgeons is still a matter of debate. Most of the medical fraternity accepts cataract surgery of ancient surgeons as couching procedure but after going through forth coming pages, the prevailing concept will prove to be a myth. It started with extra capsular extraction through small incision during the period of Sushruta Samhita but later shifted to couching like technique by Acharya Vagbhatta. Secondly, the objective of this literary research paper is to find proper co-relation of the disease cataract to those mentioned in Ancient Ayurvedic classic. Linganasha has been inadvertently taken as cataract but this is neither logical nor in accordance with classics. We find detailed description of cataract's differential diagnosis, indications, contra- indications, pre/intra/post operative procedures and complication in ancient texts of Ayurveda. Not only this, vivid description of treatment of various complications of cataract surgery are also given. Needless to say, no other surgically treatable diseases & its complications except Kaphaja Linganasha are given this much attention.

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Various types of stress not only harm the mental function, but also cause diseases by weakening body defenses. Rasayana therapy has an advantage over the conventional Kayachikitsa treatment in such conditions, as it is capable of counteracting the stress, promote the adaptogenic abilities of the body, enhance mental endurance, etc. These are the some of parameters for evaluation the rasayana effect of a drug, therefore the same have been studied to assess the rasayana effect of Ranahamsa Rasayanaya (RR). Experimental models such as forced swimming induced hypothermia and stress induced gastric ulcer formation have been carried out befitting on Charles Foster strain albino rats to determine the rasayana effect of RR. Statistically highly significant decrease in forced swimming induced hypothermia and non-significant decrease in gastric ulcer formation were observed in the treatment groups, when compared to the stress control group. These results show the probable adaptogenic and anti-stress activities of the test drug. The study results support the claims made by the Sri Lankan traditional practitioners that, the test drug is a potent rasayana formulation.

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Adhimantha is a disease which has been mentioned by Sushruta as an intense feeling of the eye, wherein eye seems to be being extracted out and churned up alongwith the involvement of the half of the head in association with specific features of the particular Dosha involved. Glaucoma is a disease which is characterized by raised intra-ocular pressure, optic disc cupping and visual field defect. The clinical study was done on 79 patients of Kaphaja Adhimantha in 4 different groups. Group A was treated with Triphaladi Varti. Group B was treated with Nayanamrita Lauha. Group C was combined group wherein both Nayanamrita Lauha and Triphaladi Varti were given. Group D was treated with placebo eye drop (Saurastra Netra Bindu). After the enrolment of the patients for this study, signs and symptoms such as dimness of vision, heaviness in head, coloured haloes, optic disc changes, IOP and visual field changes were studied before, during and after the treatment. The study indicates that combined group showed better results as compared to other groups.

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Rasamanikya is a famous drug, frequently used by Ayurvedic physicians for Vata-Kaphaja diseases like Shwasa, Kasa and Kushtha (Skin disorders). Various methods of preparation have been found described in Rasa classics. Generally it is prepared by Shuddha Haratala which is kept between two thin transparent Abharaka Patra (mica sheets) in small scale and in sharava for large scale, heated up to desired level. There are so many methods and different liquid media have been found described for Shodhana of Haratala. Therefore the methods of preparation of Rasamanikya and Shodhana process of Haratala have been validated through various experiments. Tankana-treated Haratala (T. Treated) is found best for Shodhana process and final product too i.e. Rasamanikya in terms of pharmaceutical standards i.e. Ruby in colour, along with reproducibility of fixed quality.

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Thalassemia is the commonest single gene disorder in India. About 10,000 infants with Thalassemia major are born every year. The present study was under taken with a hope to prevail better quality of life to the Thalassemic patients. Pallor being the chief complaint, a randomized controlled trial was undertaken with Dhatri Avaleha as it is specially mentioned for Pandu, Kamala & Haleemaka Roga. Children between age group of 1 to 15 years were randomly divided in two groups: Drug treated group (Group A) and Control group (Group B). Assessment was done on subjective and objective parameters after 30 and 60 days of treatment with follow up of two month. Statistically significant (P<0.01) result was obtained in Blood transfusion interval in group 'A' in comparison to group 'B'. Dhatri Avaleha may have a potential to increase blood transfusion interval and decrease secondary infection and thus it can be used as supportive therapy with modern medical management.

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Child health has assumed great significance in all over world. Its importance is being realized more and more by pediatricians and general public in developing as well as developed countries. Enuresis is defined as the voluntary or involuntary repeated discharge of urine into clothes or bed after a developmental age when bladder control should be established. The present clinical study was planned to evaluate the effect of Divyadi Yoga along with counseling in the management of Shayyamutra. Total 40 selected cases were divided into two groups, i.e. 20 in each group. One group of children were given the trial drug Divyadi Yoga (D1) with counseling and other group of children were given placebo Divyadi Yoga (D2) with counseling. Divyadi Yoga was given in the dose of 3-6 gms. twice a day with luke warm water. The result of the study showed that groups provided a highly significant.

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Chronic Obstructive Pulmonary Disease (COPD) threatens as emerging public health crisis. The two major drivers for this are the ageing of the world's population and the impressive, if deplorable, success of the multinational tobacco companies at forcing open world markets. One of the most striking aspect of COPD is that it is heterogenous. There are many different presentations with differing intensities of symptoms and even differing responses to the medication. Sorting out, what accounts for this phenomenon and how treatments can be best individualised, is of concern to both basic and clinical scientists. COPD is a leading cause of morbidity and mortality worldwide and results in a substantial economic and social burden to society. It is the sixth most common cause of death worldwide and expected to rise to third position by 2020. Several national and international agencies like WHO, GOLD, ATS, ERS etc. are working in a direction of finding some solution of this wicked problem. In Ayurvedic texts Shwasa Roga has been described having symptomatology close to COPD.A study was carried out in P.G.Deptt. of Kayachikitsa in R.G.G.P.G.Ayu.College Paprola, H. P. where the role and efficacy of two Ayurvedic formulations -Vasadi Syrup and Shwasaghna Dhuma was evaluated on 30 patients of COPD selected on the basis of fixed inclusion and exclusion criteria in two different groups. In both the groups drugs provided significant results based on subjective symptomatological criteria and objective spirometric criteria.

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Ayurvedic classics give importance to Shuddha Artava and mention that Artavadushti is one of the causative factors for infertility. Artavakshaya is not separately described as disease any where in Ayurvedic classics, of course, this doesn't desecrate Artavakshaya. Because, Acharya Charaka has quoted in Charaka Nidana Sthana, first chapter, that symptoms of a disease themselves also constitute as a disease. But sometime, because of their subordinate nature they are only symptoms and not disease. This quotation substantiates the stand of taking 'Artavakshaya' as disease in the present studies. There are many processes and methods available in Ayurvedic classics to alleviate Artavakshya. But it is yet, the on going research to find out a method of treatment, which is nearer to procurance of permanent cure without side effects. It is well known that Ayurvedic classics emphasize on both Shodhana and Shamana therapy. Since Vata plays key role in Yoniroga, Uttarbasti, being Vata shamana, is a specific treatment in diseased condition of Yoni. As Shamana therapy Kwatha preparation choose to evaluate its efficacy. In the present study total 37 patients were registered, out of them 6 patients were discontinued. One group of patients was administered Arkapushpa Taila Uttarbasti and Krishna Tila Kwatha simultaneously. It gave more significant result. Krishna Tila Kwatha was administered orally in other group. Placebo wheat powder was administered orally in third group. Uttarbasti and Kwatha were found highly effective when administered simultaneously.

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Total six samples of Karpanpatru Taila were prepared with Murchchhita and Amurchchhita Sarshapa Taila (mustard oil) by using three different liquid media i.e. Gomutra, Takra and Kanji by following classical method and analyzed. The pharmaceutical analysis revealed that the Karpanpatru Taila prepared with Murchchhita Sarshapa taila by using Kanji, Gomutra, Takra as a liquid media showed minimum loss i.e. 4.00%, 8,33% & 8.66 respectively in comparison to Amurchchhita Sarshapa Taila by using Kanji, Gomutra, Takra i.e. 5.5%, 10.68%, 12% respectively. Pharmaceutical drawbacks like excessive frothing and burning of eyes & nose were absent during the preparation of Karpanpatru Taila with Takra and Kanji while present in batch of Gomutra. Analytical study reveals that Acid value was negligible increased after even 6 month in the samples of Murchchhita Karpanpatru Taila while significant increased in the samples of Amurchchhita Karpanpatru Taila. Saponification value was decreased in the samples of Murchhita Karpanpatru Taila while increased in the samples Amurchchhita Karpanpatru taila. Microbial growth was found absent in all the samples of Karpanpatru Taila even after 6 months.

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The crude oil having lower iodine and free fatty acids values has Aamdosha properties. These properties are present due to toxic and anti-toxic compounds. These compounds can be harmful for the special diseases and may be unsaturated, saturated, open chain etc. The adulteration can take part as catalytic action for the toxic effect for the special diseases. Toxic properties of oils are removed by different ingrediants and methods. C. maxima seed tail (mst) is used with food and medicine. The present paper deals with the study of oil by refractive index and equations.

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For evaluation of the effect of Ahara on Health in relation to Matra, Desha and Kala, an interview based survey study was carried out by simple randomized selection of healthy and unhealthy individuals. It was found that consideraton of Matra, Desha and Kala in aspect of Ahara taking were found beneficial for health.

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Mineral drugs play an important role in Ayurvedic therapeutics. Looking to the superiority of the metals and minerals to that of herbal and animal drugs, the Rasavaidyas went on experimenting clinical trials over lot of metals and minerals and systematically separated some of them which were exclusively active therapeutically. Swarnamakshika is one such mineral which after proper purification and incineration become highly potent and utilised for diseases like Jwara, Pandu, Prameha, Shwasa, Kasa, Kushtha, Anidra, Apasmar etc.

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There are much more topics in our Ayurvedic classics about which we have limited knowledge. Like this an another topic is Indriya. We don't know what is indriya or what are their sites. Are the organs by which we perceive sensation called Indriya or different from them? Acharya Charaka has told five types of Indriyas, Sparshanendriya, Chakshurendriya, Ghranendriya, Rasanendriya & Shravanendriya. He also described their sites, functions, composition, and their properties. But he also told that Sparshanendriya is the main Indriya and it is present in all Indriyas. Why Charaka told that Sparshanendriya is Vyapak in all Indriyas. Is this concept wrong or right? The answer is right & this concept can be proved by following means as described in this paper.

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