Manasikabhava (psychic factors) plays an important role in etiopathogenesis & symptomatology of psychic and psychosomatic disease conditions. Psychic factors- kama (desire), krodha (anger), shoka (grief), bhaya (fear), irshya (envy) etc. within physiological limit can be defined as Manasikabhava whereas crossing the physiological limit these are termed as Manasikavikara or psychic disorders. Moreover, body and mind are interdependent to each other. The personality of an individual whether introvert or extrovert has also a role to play in the disease process.Irritable Bowel Syndrome (IBS) is a psychosomatic disease condition where motility of intestine is disturbed with altered bowel habit, lower abdominal pain with distention relieved by passes of flatus. There is no detectable organic pathology in this disease. The symptoms are markedly influenced by psychological factors with stressful life style. Though it is difficult to have correlation between IBS & any particular disease in Ayurveda but many diseases described in Ayurvedic classics resemble with symptoms commonly found in IBS. A careful review of the clinical picture of various GIT diseases, described in Ayurveda reveals that some of the disorders definitely have some clinical symptoms observed in the patients of IBS e.g. Vataja & Kaphaja Atisara, Sangrahani, Pravahika, Pakvashayagatavata. However, Grahani Dosha - a stage found in samprapti of all these diseases may be considered as IBS. These patients of IBS are evaluated for their mental health based on Hamilton's Anxiety Rating Scale, Hamilton's Depression Rating Scale & Brief Psychiatry Rating Scale along with Ayurvedic parameters. Total 30 patients selected randomly and divided into two groups were treated with: 1) Kutajadi Avaleha - a classical herbal formulation 10gm twice a day for 45 days and 2) Kutajadi Avaleha as above along with Charakokta Medhya-rasayana granules 5gm twice a day for 45 days. Better therapeutic response has been observed in abdominal pain, gaseous distention and diarrhea with significant relief in disturbed psychic factors like grief, worry, anger etc. in Medhya-rasayana group.

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Psoriasis is a skin disease having unknown etiology and of chronic nature. It is relapsing and so it is a problem for medical science also. Every year more than 9 million cases of psoriasis are reported in the world. The paper deals with the role of Amrutbhallatak Avaleha & Karanjadi Lepa in the management of Ekakushtha (Psoriasis) on more than 60 cases. The ingredients of the Avaleha are Bhallatak, Guduchi & some other herbal drugs. They are Kaphavataghna and Rasayana. All the ingredients of Karanjadi Lepa are Kandughna & Kushthaghna. The duration of treatment was 90 days and all the patients were kept under strict dietary control during the treatment. The observation of effect therapy was encouraging. The Amrutbhallatak Avaleha orally was used with Karanjadi Lepa externally have got a positive effect in comparison of placebo group, which had less recurrence. The effect of therapy is presented in detail in full paper with elaborate discussion & conclusion.

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Makaradhwaja is one of the most popular Kupipakwa preparations of Ayurvedic medicine. It is prepared by shuddha Swarna (Gold), Astasamskarita Parada (Mercury) and shuddha Gandhaka (Sulphur) in the ratio of 1:8:16 as ingredients. The present study was under taken to standardize the pharmaceutical procedure of Makaradhwaja prepared by Astasamskarita Parada on the level of temperature pattern and duration through Electric muffle furnace to obtain maximum yield. Total 28.32 % loss of Parada was observed during preparation of Astasamskara. The test sample of Makaradhwaja was prepared in three batches to maintain the Standard procedure by using specially designed vertical electric muffle furnace. 252.84g, 252.84g and 246.97g of Kajjali was used to produce the yield of Makaradhwaja 89.35g, 85.12g and 80.24g of respectively consuming time duration of 18.40 hrs, 18.20 hrs and 18.35 hrs respectively till switching off of the heating device. The average time duration required for complete process i.e. starting of heating to self-cooling stage [50΀ C] was about 37 to 39 hours.

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Powdered bark of Ficus recemosa Linn. was found to contain an active glycoside along with sterols, hydrocarbons, sugars and amino acids. Bioactivaty studies on the glycoside constituent P - β - d glucosyloxy benzoic acid showed antiinflammalory, antacid and antibacterial activities.

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